The Influence of a Temporary Cessation and Reperfusion of Intestinal Blood Flow on the Level of Hepatic Lipid Peroxides
The liver is an organ with a very high metabolic rate and thereby also a target for the formation and activity of free oxygen radicals. Most substances to be detoxified reach the liver as they progress from the intestinal circulation through the portal vein. During the continued inflow of such substances and by local processes, a certain amount of lipid peroxides is generated under the influence of simultaneously produced free oxygen radicals. Such lipid peroxides react with thiobarbituric acid in the same way as malondialdehyde. Thus the content of lipid peroxides can be expressed in terms of malondialdehyde.
KeywordsLipid Peroxide Superior Mesenteric Artery Intestinal Tissue Intestinal Blood Flow Free Oxygen Radical Scavenger
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