Localized Heterogeneity of Red Cell Velocity in Skeletal Muscle at Rest and After Contraction

  • Karel Tyml
  • Christopher G. Ellis
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)


Heterogeneity of blood flow in the microcirculation is one of the key parameters that determine oxygenation of tissue. The degree of heterogeneity will dictate the degree of mismatch between the convective transport of materials within the microvessels and the diffusive transport from blood to tissue. Although heterogeneity has been recognized as one of the key features of the microcirculation, it has not been measured in sufficient detail (Duling and Damon, 1987).


Surface Volume Sartorius Muscle Longitudinal Strip Asymmetry Ratio Capillary Recruitment 
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  1. Damon, D.H., and Duling, B.R. (1986). Distribution of red cells within and among capillary units of striated muscle. Fed. Proc. 45(4): 1157 (Abstract).Google Scholar
  2. Duling, B.R., and Damon, D.H. (1987). An examination of the measurement of flow heterogeneity in striated muscle. Circ. Res. 60(1): 1–13.PubMedGoogle Scholar
  3. Koller, A., Dawant, B., Lin, A., Popel, A.S., and Johnson, P.C. (1987). Quantitative analysis of arteriolar network architecture in cat sartorius muscle. Am. J. Physiol. 253: H154–H164PubMedGoogle Scholar
  4. Lund, N., Damon, D.H., Damon, D.N., and Duling, B.R. (1987). Capillary grouping in hamster tibialis anterior muscles: flow patterns, and physiological significance. Int. J. Microcirc: Clin. Exp. 5:359–372.Google Scholar
  5. Tyml, K. (1986). Capillary recruitment and heterogeneity of microvascular flow in skeletal muscle before and after contraction. Microvasc. Res. 32: 84–98.PubMedCrossRefGoogle Scholar
  6. Tyml, K., and Ellis, C.G. (1982). Evaluation of the flying spot technique as a television method for measuring red cell velocity in microvessels. Int. J. Microcirc: Clin. Exp. 1:145–155.Google Scholar
  7. Tyml, K., and Mikulash, K. (1988). Evidence for increased perfusion heterogeneity in skeletal muscle during reduced flow. Microvasc. Res. 35: 316–324.PubMedCrossRefGoogle Scholar
  8. Vrielink, H.H.E.O., Slaaf, D.W., Tangelder, G.J., and Reneman, R.S. (1987). Does capillary recruitment exist in young rabbit skeletal muscle? Int. J. Microcirc: Clin. Exp. 6: 321–332.Google Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Karel Tyml
    • 1
  • Christopher G. Ellis
    • 1
  1. 1.Department of Medical BiophysicsUniversity of Western Ontario, and The Robarts Research InstituteLondonCanada

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