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Spatial and Temporal Variability of Blood Flow in Stimulated Dog Gastrocnemius Muscle

  • J. Piiper
  • C. Marconi
  • N. Heisler
  • M. Meyer
  • H. Weitz
  • D. R. Pendergast
  • P. Cerretelli
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)

Abstract

Estimations of muscle blood flow distribution by radioactive microsphere trapping have shown a widely uneven distribution in the isolated-perfused gastrocnemius of the dog (Piiper et al., 1985) and in leg muscles (vastus lateralis, gastrocnemius and triceps brachii) of intact dogs (Pendergast et al., 1985). Moreover, the blood flow heterogeneity, already large at rest, was found to increase both during artificial stimulation and natural exercise.

Keywords

Gastrocnemius Muscle Muscle Blood Flow Blood Flow Distribution Blood Flow Heterogeneity Muscle Piece 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Bassingthwaighte, J.B., Malone, M.A. Moffett, T.C., King, R.B., Little, S.E., Linke, J.M. and Krohn, K.A., 1987, Validity of microsphere depositions for regional myocardial flows. Am. J. Physiol. 253: H184–H193.PubMedGoogle Scholar
  2. Cerretelli, P., Marconi, C., Pendergast, D., Meyer, M., Heisler, N., and Piiper, J., 1984, Blood flow in exercising muscles by xenon clearance and by microsphere trapping, J. Appl. Physiol. 56: 24–30.PubMedGoogle Scholar
  3. Fung, Y.C., 1973, Stochastic flow in capillary blood vessels, Microvasc. Res. 5: 34–48.PubMedCrossRefGoogle Scholar
  4. Gaehtgens, P., Pries, A. and Albrecht, K.H., 1979, Model experiments on the effect of bifurcations on capillary blood flow and oxygen transport, Pflügers Arch. 380: 115–120.PubMedCrossRefGoogle Scholar
  5. King, R.B., Bassingthwaighte, J.B., Hales, J.R.S. and Rowell, L.B., 1985, Stability of heterogeneity of myocardial blood flow in normal awake baboons, Circ. Res. 57: 285–295.PubMedGoogle Scholar
  6. Laughlin, M.H. and Armstrong, R.B., 1983, Rat muscle blood flows as a function of time during prolonged slow treadmill exercise, Am. J. Physiol. 244: H814–H824PubMedGoogle Scholar
  7. Laughlin, M.H., Mohrman, S.J. and Armstrong, R.B., 1984, Muscular blood flow distribution patterns in the hindlimb of swimming rats, Am. J. Physiol. 246: H398–H403PubMedGoogle Scholar
  8. Little, S.E. and Bassingthwaighte, J.B., 1983, Plasma-soluble marker for intraorgan regional flows, Am. J. Physiol. 245: H707–H712.PubMedGoogle Scholar
  9. Mackie, B.G. and Terjung, R.L., 1983, Blood flow to different skeletal muscle fiber types during contraction, Am. J. Physiol. 245: H265–H275.PubMedGoogle Scholar
  10. Marconi, C., Heisler, N., Meyer, M., Weitz, H., Pendergast, D.R., Cerretelli, P. and Piiper, J., 1988, Blood flow distribution and its temporal variability in stimulated dog gastrocnemius muscle, Respir. Physiol. (in press).Google Scholar
  11. Pendergast, D.R., Krasney, J.A., Ellis, A., McDonald, B., Marconi, C. and Cerretelli, P., 1985, Cardiac output and muscle blood flow in exercising dogs, Respir. Physiol. 61: 317–326.PubMedCrossRefGoogle Scholar
  12. Piiper, J., di Prampero, P.E. and Cerretelli, P., 1968, Oxygen debt and high-energy phosphates in gastrocnemius muscle of the dog, Am. J. Physiol. 215: 523–531.PubMedGoogle Scholar
  13. Piiper, J., Pendergast, D.R., Marconi, C., Meyer, M., Heisler, N. and Cerretelli, P., 1985, Blood flow distribution in dog gastrocnemius muscle at rest and during stimulation, J. Appl. Physiol. 48: 2068–2074.Google Scholar
  14. Yipintsoi, T., Dobbs, Jr., W.A., Scanlon, P.D., Knopp, T.J. and Bassingthwaighte, J.B., 1973, Regional distribution of diffusible tracers and carbonized microspheres in the left ventricle of isolated dog hearts, Circ. Res. 33: 573–587.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • J. Piiper
    • 1
    • 2
    • 3
    • 4
  • C. Marconi
    • 1
    • 2
    • 3
    • 4
  • N. Heisler
    • 1
    • 2
    • 3
    • 4
  • M. Meyer
    • 1
    • 2
    • 3
    • 4
  • H. Weitz
    • 1
    • 2
    • 3
    • 4
  • D. R. Pendergast
    • 1
    • 2
    • 3
    • 4
  • P. Cerretelli
    • 1
    • 2
    • 3
    • 4
  1. 1.Abteilung PhysiologieMax-Planck-Institut für experimentelle MedizinGöttingenGermany
  2. 2.Département de PhysiologieEcole de Médecine, Université de GenèveGenevaSwitzerland
  3. 3.Consiglio Nazionale delle RicercheCentro Studi di Fisiologia del Lavoro MuscolareMilanItaly
  4. 4.Department of PhysiologyState University of New York at BuffaloBuffaloUSA

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