Near Infrared Determined Cerebral Transit Time and Oxy- and Deoxyhemoglobin Relationships During Hemorrhagic Hypotension in the Dog

  • Marco Ferrari
  • David A. Wilson
  • Daniel F. Hanley
  • Richard J. Traystman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)


Many recent papers suggest that in patients with cerebrovascular diseases, cerebral blood flow (CBF) measurement alone is a poor indicator of hemodynamic reserve (Gibbs et al., 1984). A usual finding of positron emission tomography studies is a fall of the CBF/cerebral blood volume (CBV) ratio, mathematically equivalent to an increase of the mean transit time (MTT) (Zierler, 1965).


Cerebral Blood Flow Cerebral Perfusion Pressure Mean Transit Time Superior Sagittal Sinus Clearance Curve 


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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Marco Ferrari
    • 1
  • David A. Wilson
    • 3
  • Daniel F. Hanley
    • 3
  • Richard J. Traystman
    • 2
    • 3
  1. 1.Department of Biomedical Sciences and TechnologyBiometrics, University of L’AquilaL’AquilaItaly
  2. 2.Physiopathology Laboratory, Istituto Superiore di SanitaRomeItaly
  3. 3.Department of Anesthesiology/Critical Care MedicineThe Johns Hopkins UniversityBaltimoreUSA

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