Precapillary O2 Loss and Arteriovenous O2 Diffusion Shunt are Below Limit of Detection in Myocardium

  • C. R. Honig
  • T. E. J. Gayeski
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)


Is venous PO2 an index of tissue PO2, of end capillary PO2, or neither of these because of diffusive shunting from arterioles to venules? To evaluate diffusive shunting and venous PO2 in myocardium we determined hemoglobin (Hb) saturation in arterioles and venules and myoglobin (Mb) saturation in individual subepicardial myocytes by use of a cryomicrospectrophotometric method (Gayeski, 1981, Degner and Gayeski, 1987).


Intracellular Action Potential Venule Diameter Transmural Gradient Saturation Gradient Measuring Diaphragm 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • C. R. Honig
    • 1
  • T. E. J. Gayeski
    • 1
  1. 1.The University of Rochester, School of Medicine and DentistryRochesterUSA

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