Tissue Oxygen Tension in the Cerebral Cortex of the Rabbit

  • M. Fennema
  • J. N. Wessel
  • N. S. Faithfull
  • W. Erdmann
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)


For the normal function and survival of an organism, a continuous supply of energy is necessary. Without energy nearly all physiological processes, such as electrolyte pumping, could not take place; in other words, Cannon’s ‘homeostasis’ would not exist. On the cellular level, oxydative phosphorylation produces energy. This process is maintained by an almost continuous supply of oxygen. Therefore oxygen is the decisive vital parameter in (human) life. Disturbance in tissue respiration causes a decrease in cellular function, reversible functional breakdown and, finally, irreversible cell death. One of the most common hazards during the perinatal period is hypoxia. Prolonged hypoxia may cause permanent brain damage.


Cerebral Tissue Gold Wire Tissue Oxygen Tension Giant Neuron Permanent Brain Damage 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • M. Fennema
    • 1
  • J. N. Wessel
    • 2
  • N. S. Faithfull
    • 3
  • W. Erdmann
    • 1
  1. 1.Departments of AnaesthesiaErasmus UniversityRotterdamThe Netherlands
  2. 2.Departments of NeurologyErasmus UniversityRotterdamThe Netherlands
  3. 3.University Department of Anaesthetics, Hope HospitalManchesterUK

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