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A CCD Spectrophotometer to Quantitate the Concentration of Chromophores in Living Tissue Utilising the Absorption Peak of Water at 975 nm

  • M. Cope
  • D. T. Delpy
  • S. Wray
  • J. S. Wyatt
  • E. O. R. Reynolds
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)

Abstract

Optical spectroscopy has long been used to study the oxygenation of living tissue in-vivo. It is possible to detect concentration changes of naturally occurring chromophores whose absorption spectra are affected by the presence of oxygen, such as haemoglobin and the cytochrome enzymes.

Keywords

Exchange Transfusion Array System Readout Noise Photo Diode Array Fibre Optic Bundle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Brunori, M., Antonini, E., and Wilson, M.T., 1981, Cytochrome C Oxidase: An overview of recent work, in: “Metal ions in Biological Systems”, H. Siegel, ed., Dekker, N.Y.Google Scholar
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  5. Wray, S., Cope, M., Delpy, D.T., Wyatt, J.S., and Reynolds, E.O.R., 1988, Characterization of the near infrared absorption spectra of cytochrome aa3 and haemoglobin for the non-invasive monitoring of cerebral oxygenation, Biochim. Biophvs, Acta. 933:184–192.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • M. Cope
    • 1
  • D. T. Delpy
    • 1
  • S. Wray
    • 2
  • J. S. Wyatt
    • 3
  • E. O. R. Reynolds
    • 3
  1. 1.Department of Medical Physics and BioengineeringUniversity College LondonLondonUK
  2. 2.Department of PhysiologyUniversity College LondonLondonUK
  3. 3.Department of PaediatricsUniversity College LondonLondonUK

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