The Effect of Fluorocarbon Emulsion on Placental Insufficiency
Oxygen-carrying plasma substitutes based on emulsified perfluorocarbons (PFCs) have undergone extensive experimental and clinical evaluation over the last 10 years. Though they were originally introduced as “artificial blood”, it is clear that their use will probably be largely in more specialised areas such as improvement of microcirculatory oxygenation in, for instance, the treatment of myocardial and cerebral ischaemia (Böse et al. 1986; Faithfull et al. 1986) or improvement of oxygenation, and hence radiosensitivity, of malignant tumours (Teicher and Rose 1984).
KeywordsUterine Horn Foetal Weight Placental Insufficiency Isolate Lung Perfusion Fluorocarbon Emulsion
Unable to display preview. Download preview PDF.
- Erdmann, W., 1982. 02 Diffusion coefficients. In:Oxygen Carrying Colloidal Blood Substitutes, Eds. Frey R, Beisbarth H, Stossek K. W Zuckschwerdt Verlag, Munich. p 143.Google Scholar
- Faithfull, N.S., Fennema, M., Erdmann, W., Lapin, R., Smith, A.R., van Alphen, W., Essed, C.E. and Trouwborst, A., 1985. Tissue oxygenation by fluorocarbons. Adv. Exp. Med. Biol. 180:569.Google Scholar
- Faithfull, N.S. and Cain, S.M., 1988. Cardiorespiratory consequences of fluorocarbon rections in dogs. Biomat. Art. Cells and Art. Organs 16:463.Google Scholar
- Naito, R., Fujita, Y. and Suyama, T., 1978. Studies on teratogenicity of Fluosol-DA in rats. In: Proceedings of the Symposiun on Research on Perfluorochemicals in Medicine and Biology. V. Novakova and L.-O. Plantin, eds. GOTAB, Stockholm.Google Scholar