Calculation of Oxygen Pressures and Fluxes in a Flat Plane Perpendicular to Any Capillary Distribution
Most modelling of oxygen transport in tissue has been based on the classical Krogh-Erlang equation (Krogh, 1919), which describes oxygen diffusion in any circular cross-section of a spherical cylinder around a capillary. Extensions like facilitated diffusion and non-zero-order oxygen consumption can be built in and combined with blood flow and capillary spacing heterogeneity (Turek et al., this volume). Other models are based on computer simulations (Federspiel, 1986; Popel et al., 1986; Groebe, 1987), with the disadvantage of describing only specific situations; thus making application in real heterogeneous tissue impossible.
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