Calculation of Oxygen Pressures and Fluxes in a Flat Plane Perpendicular to Any Capillary Distribution

  • Louis Hoofd
  • Zdenek Turek
  • Jos Olders
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 248)

Abstract

Most modelling of oxygen transport in tissue has been based on the classical Krogh-Erlang equation (Krogh, 1919), which describes oxygen diffusion in any circular cross-section of a spherical cylinder around a capillary. Extensions like facilitated diffusion and non-zero-order oxygen consumption can be built in and combined with blood flow and capillary spacing heterogeneity (Turek et al., this volume). Other models are based on computer simulations (Federspiel, 1986; Popel et al., 1986; Groebe, 1987), with the disadvantage of describing only specific situations; thus making application in real heterogeneous tissue impossible.

Keywords

Permeability Resis 

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Louis Hoofd
    • 1
  • Zdenek Turek
    • 1
  • Jos Olders
    • 1
  1. 1.Dept. PhysiologyUniversity of NijmegenNijmegenThe Netherlands

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