Advertisement

A Model for Bidirectional Transduction in Outer Hair Cells

  • S. T. Neely
Part of the NATO ASI Series book series (NSSA)

Abstract

There is considerable evidence for the existence of a cochlear amplifier which serves to increase the sensitivity and frequency selectivity of the cochlea to low intensity sounds (Davis, 19S3). Earlier models of traveling-wave amplification in the cochlea used negative damping components to supply the additional energy used to power the cochlear amplifier (Kim, et al., 1980; de Boer, 1983; Koshigoe and Tubis, 1983). The negative damping models are now being replaced by more realistic feedback force models in which the fast motile response of the outer hair cell is implicated as the driving force for the cochlear amplifier (Geisler, 1986; Zwicker, 1986; Neely and Kim, 1987).

Keywords

Outer Hair Cell Basilar Membrane Tuning Curve Otoacoustic Emission Hair Bundle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Allen, J.B. (1980). Cochlear micromechanics — A physical model of transduction. J. Acoust. Soc. Am. 68, 1660–1679.PubMedCrossRefGoogle Scholar
  2. Ashmore, J.F. (1987). A fast motile response in guinea-pig outer hair cells: The cellular basis of the cochlear amplifier. J. Physiol. 388, 323–347.PubMedGoogle Scholar
  3. Ashmore, J.F. (1988). What is the stimulus for outer hair cell motility? In: Basic Issues in Hearing (Eds: Duifhuis, H., Hoorst, J.W., and Wit H.P.), Academic Press, London,.Google Scholar
  4. de Boer, E. (1983). No Sharpening? A challenge for cochlear mechanics. J. Acoust. Soc. Am. 73, 567–573.PubMedCrossRefGoogle Scholar
  5. Desmedt, J.E. and Robertson, D. (1975). Ionic mechanism of the efferent olivo-cochlear inhibition studied by perfusion in the cat. J. Physiol. 247, 407–428.PubMedGoogle Scholar
  6. Brownell, W.E., Bader, C.E., Bertrand, D., and de Ribaupierre, Y. (1985). Evoked mechanical responses of isolated cochlear outer hair cells. Science 227, 194–196.PubMedCrossRefGoogle Scholar
  7. Brownell, W.E., and Kachar, B. Outer hair cell motility: A possible electro-kinetic mechanism. In: Peripheral Auditory Mechanisms (Eds: Allen, J.B., Hall, J.L., Hubbard, A., Neely, S.T., and Tubis, A.) Springer-Verlag, Munich, pp.369-376.Google Scholar
  8. Davis, H. (1983). An active process in cochlear mechanics, Hearing Res. 9, 1–49.CrossRefGoogle Scholar
  9. Geisler, C.D. (1986). A model of the effect of outer hair cell motility on cochlear vibrations. Hearing Res. 24, 125–132.CrossRefGoogle Scholar
  10. Gitter, A.H., and Zenner, H-P. (1988). Auditory transduction steps in single inner and outer hair cells. In: Basic Issues in Hearing (Eds: Duifhuis, H., Hoorst, J.W., and Wit H.P.), Academic Press, London.Google Scholar
  11. Hudspcth, A.J., and Corey, D.P. (1977). Sensitivity, polarity, and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli. Proceedings of the National Academy of Science, (USA) 74, 2407–2411.CrossRefGoogle Scholar
  12. Kiang, N.Y.S., and Moxon, E.C. (1972). Physiological considerations in artificial stimulation of the inner ear. Ann. Otol. Rhinol. Laryngol. 81, 714–730.PubMedGoogle Scholar
  13. Kim, D.O., Neely, S.T., Molnar, C.E., and Matthews, J.W. (1980). An active cochlear model with negative damping in the cochlear partition: Comparison with Rhode’s ante-and post-mortem results. In: Psychological, Physiological and Behavioral Studies in Hearing (Eds: van den Brink, G., and Bilsen, F.A.), University Press, Delft, The Netherlands, pp. 7–14.CrossRefGoogle Scholar
  14. Koshigoe, S. and Tubis, A. (1983). Frequency-domain investigations of cochlear stability in the presence of active elements. J. Acoust. Soc. Am. 73, 1244–1248.PubMedCrossRefGoogle Scholar
  15. Mott, J.B., Norton, S.J., Neely, S.T., and Warr, S.T. (1988). Changes in spontaneous otoacoustic emissions produced by acoustic stimulation of the contralateral ear. (In preparation.).Google Scholar
  16. Neely, S.T. (1988). Transient responses in an active, nonlinear model of cochlear mechanics. In: Basic Issues in Hearing (Eds: Duifhuis, H., Hoorst, J.W., and Wit H.P.), Academic Press, London.Google Scholar
  17. Neely, S.T., and Kim, D.O. (1987) A model for active elements in cochlear biomechanics. J. Acoust. Soc. Am. 79, 1472–1480.CrossRefGoogle Scholar
  18. Warr, W.B. and Guinan, J.J. (1979). Efferent innervation of the organ of Corti: two separate systems. Brain Res. 173, 152–155.PubMedCrossRefGoogle Scholar
  19. Weiss, T.F. (1982). Bidirectional transduction in vertebrate hair cells: A mechanism for coupling mechanical and electrical processes. Hearing Res. 7, 353–360.CrossRefGoogle Scholar
  20. Zwicker, E. (1986). A hardware cochlear nonlinear preprocessing model with active feedback. J. Acoust. 80, 146–153.CrossRefGoogle Scholar
  21. Whitehead, M.L., Wilson, J.P. and Baker, R.J. (1986). The effects of temperature on otoacoustic emission tuning properties. In: Auditory Frequency Selectivity (Eds. Moore, B.C.J. and Patterson, R.D.), Plenum, New York, pp 39–46.Google Scholar
  22. Sutton, G.J. and Wilson, J.P. (1983) Modelling cochlear echoes: the influence of irregularities in frequency mapping on summed cochlear activity. In: Mechanics of Hearing, Eds: E. de Boer and M.A. Viergever, Delft Univ. Press, Delft, pp. 83–90.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • S. T. Neely
    • 1
  1. 1.Boys Town National InstituteOmahaUSA

Personalised recommendations