Tip-Link Organization in Relation to the Structure and Orientation of Stereovillar Bundles
The linkages between stereovilli (stereocilia) of hair cells have been implicated both in the mechanical properties of the bundles and in the transmission of stimulus-induced movements to the individual mechanotransducer channels (e.g. Flock and Strelioff, 1984; Pickles et al., 1984; Hudspeth, 1985). Here, we describe new observations on the fine structure of the tip links between stereovilli. We also show that the spatial organization of the tip links in bundles of different conformations in a variety of species is appropriate for a role in transduction.
KeywordsHair Cell Actin Filament Outer Hair Cell Bilateral Symmetry Hair Bundle
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