Mechano-Electrical Transduction in Turtle Hair Cells
The initial step in hair cell transduction involves coordinated flexion of an array of microvilli, the hair bundle, which gates a membrane conductance enabling a transducer current to flow into the cell (Hudspeth & Corey, 1977; Ohmori, 1985). Although the ionic selectivity of the transducer conductance is known (Corey & Hudspeth, 1979; Ohmori, 1985), the events leading to activation of the channel are not fully understood, and there is no consensus even on the precise form of relationship between bundle displacement and transducer current. Here we present some observations on the transduction process in turtle hair cells measured both directly in isolated cells under voltage clamp and indirectly from receptor potentials in the intact ear.
KeywordsHair Cell Sound Pressure Receptor Potential Hair Bundle Cochlear Hair Cell
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