Biochemical Properties of Unusual Polyamines Found in an Extreme Thermophile, Thermus thermophilus

  • Tairo Oshima
  • Nobuko Hamasaki
  • Taketoshi Uzawa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 250)


An extreme thermophile, Thermus thermophilus was isolated from a Japanese hot spring (Oshima and Imahori, 1974) which can grow in a temperature range of 50 °C to 85 °C. This unique microorganism produces a variety of polyamines. So far thirteen polyamines and two diamines have been detected; their trivial names and chemical structures are listed in Table 1. Most of these polyamines have been extracted from the thermophile, purified and identified by NMR, mass, and IR spectra. Their identification was finally confirmed by chemical synthesis (Oshima, 1983A). Unusually long polyamines and branched polyamines produced by the thermophile may play important roles in the thermophile cells and may exhibit unique activities in biochemical reactions in vitro.


Thermophilic Bacterium Butyl Group Lithium Aluminum Hydride Extreme Thermophile Thermus Thermophilus 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Tairo Oshima
    • 1
  • Nobuko Hamasaki
    • 1
  • Taketoshi Uzawa
    • 1
  1. 1.Department of Life ScienceTokyo Institute of TechnologyNagatsuta, Yokohama 227Japan

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