Interaction of Polyamines with Phospholipids: Spermine and Ca2+ Competition for Phosphatidylserine Containing Liposomes

  • Bruna Tadolini
  • Gabriele Hakim
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 250)


The ability of polyamines to interact with biological membranes was first described by Tabor who showed that polyamines aggregate subcellular organelles and stabilize mitochondria and protoplasts (1). Since then many reports pointed out a possible involvement of polyamines on membrane structure, metabolism and function.


Phosphatidic Acid Phospholipid Vesicle Inorganic Cation Acidic Phospholipid Secondary Plot 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Bruna Tadolini
    • 1
  • Gabriele Hakim
    • 1
  1. 1.Dipartimento di BiochimicaUniversità di BolognaBolognaItaly

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