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Physico-Chemical and Immunological Properties of Bovine Liver 5′-Deoxy-5′-Methylthioadenosine Phosphorylase

  • Fulvio Della Ragione
  • Adriana Oliva
  • Massimo Fioretti
  • Gian Luigi Russo
  • Rosanna Palumbo
  • Vincenzo Zappia
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 250)

Abstract

The search for specific enzymatic reactions which can clearly differentiate normal mammalian cells from both malignant cells and infective microorganisms represents a major strategy for the development of selective therapeutical approaches. In particular, the intensive research carried out in the past on purine and pyrimidine metabolism has yielded a very rich harvest of drugs effective in the treatment of malignancy as well as of parasitic diseases.

Keywords

Human Placenta Bovine Liver Purine Nucleoside Phosphorylase Phosphorylase Activity Frictional Ratio 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Fulvio Della Ragione
    • 1
  • Adriana Oliva
    • 1
  • Massimo Fioretti
    • 1
  • Gian Luigi Russo
    • 1
  • Rosanna Palumbo
    • 1
  • Vincenzo Zappia
    • 1
  1. 1.Department of Biochemistry of Macromolecules, First Medical SchoolUniversity of NaplesNaplesItaly

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