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Dose Fractionation in Neutron Capture Therapy for Malignant Melanoma

  • B. J. Allen
  • J. K. Brown
Part of the Basic Life Sciences book series (BLSC, volume 50)

Abstract

Australia is entering a joint clinical trial with Japan for thermal Neutron Capture Therapy of selected patients with superficial local recurrent, local advanced and isolated metastatic malignant melanoma. The para-boronophenylalanine (BPA) compound will be used with a neutron fluence of about 1013 neutrons per cm2, to be delivered in a single dose. While in the initial trials of NCT, the single dose is a practical procedure, there may be advantages in dose fractionation, and these are considered in this paper.

Keywords

Boron Atom Hypoxic Cell Boron Neutron Capture Therapy Dose Fraction Neutron Radiography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • B. J. Allen
    • 1
  • J. K. Brown
    • 1
  1. 1.Australian Nuclear Science & Technology OrganisationLucas Heights Research LaboratoriesMenaiAustralia

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