Blood-Brain-Barrier Impairment after Irradiation: Implication in Boron Neutron Capture Therapy

  • V. Grégoire
  • Andrè Keyeux
  • Andrè Wambersie
Part of the Basic Life Sciences book series (BLSC, volume 50)


The rationale of boron neutron capture therapy (BNCT) in brain tumors rests on the assumption that the boronated compounds will not be incorporated in the normal CNS protected by the tight blood-brain barrier (BBB) but will enter the tumor at the level at which the BBB is impaired.l


Brain Tumor Tight Junction Brain Damage Boron Neutron Capture Therapy Brain Irradiation 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • V. Grégoire
    • 1
  • Andrè Keyeux
    • 1
  • Andrè Wambersie
    • 1
  1. 1.Unité de Radiobiologie et de RadioprotectionUniversité Catholique de LouvainBrusselsBelgium

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