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Swine Skin: A Model to Evaluate Dose Recovery from Different Radiations

  • J. O. Archambeau
Part of the Basic Life Sciences book series (BLSC, volume 50)

Abstract

Unacceptable scalp and facial skin reactions were produced during the first clinical trials of neutron capture therapy. These complications resulted because the half-value layer (HVL) of thermal neutrons in tissue is small (about 1.8 cm), and the boron-10 partition between the blood/skin and cancer located several centimeters below the surface was poor. As a consequence, when a therapeutic dose was delivered to the cancer at depth, the dose from the adventitious gamma, fast-neutron and capture radiations to the skin exceeded the limits of tolerance.1

Keywords

Thermal Neutron Neutron Beam Relative Biological Effectiveness Dose Contribution Mixed Beam 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • J. O. Archambeau
    • 1
  1. 1.Department of Radiation BiologyLoma Linda UniversityLoma LindaUSA

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