Prediabetes pp 403-413 | Cite as

Strategies for Primary Prevention of Non-Insulin Dependent Diabetes Mellitus

  • Jaako Tuomilehto
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 246)


Non-insulin dependent diabetes mellitus (NIDDM) is a disease with poorly understood natural history and severe long-term complications, and it is associated with large human and economic burden and costs. Epidemiologic data from various parts of the world suggest that NIDDM is increasing in most populations and in some of them it has already reached epidemic proportions (1). Diabetes seriously affects the quality of life because of its complications and the life of diabetic patients is clearly shortened. These facts make the question of preventing NIDDM important.


Glucose Tolerance Impaired Glucose Tolerance Gestational Diabetes Normal Glucose Tolerance Population Attributable Risk 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Zimmet, P., 1982, Type 2 (non-insulin-dependent) diabetes - an idemiological overview. Diabetologia 22: 399–411.PubMedCrossRefGoogle Scholar
  2. 2.
    Joslin, E.P., 1982, The prevention of diabetes mellitus. JAMA 76: 79–84.CrossRefGoogle Scholar
  3. 3.
    Tuomilehto, J., Wolf, E., 1987, Primary prevention of diabetes mellitus. Diabetes Care 10: 238–248.PubMedCrossRefGoogle Scholar
  4. 4.
    Kobberling, J., Tillil, H., 1982, Empirical risk figures for first-degree relatives of non-insulin-dependent diabetes. In: Kobberling, J., Tattersall, R., eds.. The Genetics of Diabetes Mellitus. London: Academic Press, 201–210.Google Scholar
  5. 5.
    Barnett, A.H., Eff, C., Leslie, R.D.G., Pyke, D.A., 1981, Diabetes in identical twins - a study of 200 pairs. Diabetologia 20: 87–93.PubMedCrossRefGoogle Scholar
  6. 6.
    Tuomilehto, J., Nissinen, A., Kivela, S-L et al., 1986, Prevalence of diabetes mellitus in elderly men aged 65 to 84 years in eastern and western Finland. Diabetologia 29: 611–615.PubMedCrossRefGoogle Scholar
  7. 7.
    Zimmet, P., Taylor, R., King, H., 1982, Diabetes in the Pacific: An Epidemiological Perspective. Eschwage E., ed.. Advances in Diabetes Epidemiology, INSERM S3miposium, No. 22. New York: Elsevier.Google Scholar
  8. 8.
    Knowler, W.C., Pettit, D.J., Savage, P.J., Bennett, P.H., 1981, diabetes in Pima Indians: contributions of obesity and parental diabetes. Am J Epidemiol 113: 114–156.Google Scholar
  9. 9.
    Vague, J., 1956, The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, arteriosclerosis, gout and uric calculus disease. Am J Clin Nutr 4: 20–34.PubMedGoogle Scholar
  10. 10.
    Frisch, R.E., Wyshak, G., Albright, T.E., Albright, N.L., Schiff, I., 1986, Lower prevalence of diabetes in female former college athletes compared with nonathletes. Diabetes 35: 1101–1105PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Jaako Tuomilehto
    • 1
  1. 1.Department of EpidemiologyNational Public Health Institute HelsinkiFinland

Personalised recommendations