Development of Diabetes in the Non-Obese NIDDM Rat (GK Rat)
We produce spontaneously diabetic rats from normal rats by repeating the selective breeding using glucose intolerance as the selection index. The rats are called GK rats and now we have the 37th generation. In this paper, characteristic features, insulin secretion and the effect of obesity will be presented.
KeywordsGlucose Intolerance Nerve Conduction Velocity Selective Breeding Insulin Content Nerve Fiber Density
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