Prediabetes pp 297-303 | Cite as

Kidney Disease in KK Mice: Effect of Glyburide

  • R. A. Camerini-Davalos
  • A. S. Reddi
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 246)


In previous publications (1,2) and in the present volume, we reported that the KK mouse represents an ideal animal model for the study of kidney disease in Type II diabetes. We report here the effect of early and late glyburide (a second generation oral hypoglycemic compound) treatment on glucose metabolism and its relationship to glomerulosclerosis in KK mice.


Oral Glucose Tolerance Test Blood Sugar Level Glyburide Treatment Swiss Albino Mouse Improve Glucose Tolerance 


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • R. A. Camerini-Davalos
    • 1
  • A. S. Reddi
    • 2
  1. 1.Department of Medicine, Metropolitan Hospital Research CenterNew York Medical CollegeNew YorkUSA
  2. 2.Department of MedicineUMDNJ - New Jersey Medical SchoolNewarkUSA

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