Prediabetes pp 255-258 | Cite as

Development of Diabetes in Identical Twins

  • D. A. Pyke
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 246)


The value of studies in identical (monozygotic) twins lies as much in what they refute as in what they confirm. Thus if a pair of twins resembles each other in respect of a condition that does not prove that the condition is inherited, but if they differ from each other then the condition cannot be inherited.


Beta Cell Twin Pair Identical Twin Islet Cell Antibody Discordant Pair 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Barnett, A.H., Eff, C., Leslie, R.D.G., Pyke, D.A., 1981, Diabetes in Identical Twins: A study of 200 pairs. Diabetologia 20, 87.PubMedCrossRefGoogle Scholar
  2. 2.
    Johnston, C., Pyke, D.A., Cudworth, A.G., Wolf, E., 1983, HLA-DR typing in identical twins with insulin-dependent diabetes. British Medical Journal 286, 253.PubMedCrossRefGoogle Scholar
  3. 3.
    Millward, B.A., Welsh, K.I., Leslie, R.D.G., Pyke, D.A. Demaine, A.G., 1987, T-cell receptor beta chain polymorphisms are associated with insulin-dependent diabetes. Clin. exp. Immunol. 70, 152–157.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • D. A. Pyke
    • 1
  1. 1.King’s College HospitalLondonUK

Personalised recommendations