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Prediabetes pp 241-253 | Cite as

Genetic and Humoral Markers in IDDM Patients and their Families

  • Maximino Ruiz
  • Felix E. Puchulu
  • Alejo Florin Christensen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 246)

Abstract

The association between some HLA and insulin-dependent diabetes was demonstrated by Nerup et al1 when they observed a high prevalence of HLA B8 B15 in this type of diabetes. Afterwards, several authors2 demonstrated that there are a linkage disequilibrium of the HLA B8 and B15 and the HLA DR3 and DR4, and that these are the principal genetic markers.

Keywords

Beta Cell Insulin Dependent Diabetes Islet Cell Antibody Congenital Rubella Syndrome Proinsulin Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Maximino Ruiz
    • 1
  • Felix E. Puchulu
    • 1
  • Alejo Florin Christensen
    • 1
  1. 1.Fundacion Argentina de Diabetes y Enfermedades Metabolicas (FADEM) Seccion Diabetologia of Hospital de Clinicas “Jose de San Martin ”Centro de Educacion Medica e Investigaciones Clinicas (CEMIC)Argentina

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