Prediabetes pp 167-174 | Cite as

Low Insulin Response: A Marker Of Prediabetes

  • Suad Efendic
  • Valdemar Grill
  • Rolf Luft
  • Alexandre Wajngot
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 246)


It is generally accepted that genetic factors play a decisive role in the development of non-insulin dependent diabetes (NIDDM). Accordingly, the manifest disease develops gradually from a genetically determined initial stage, prediabetes, over a stage characterized by a decrease in glucose tolerance only. This process might be slow or rapid, possibly dependent on the type and ‘weight’ of the genetic trait as well as on factors precipitating the disease.


Glucose Tolerance Insulin Release Insulin Response Plasma Insulin Response Hyperglycemic Clamp 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Suad Efendic
    • 1
  • Valdemar Grill
    • 1
  • Rolf Luft
    • 1
  • Alexandre Wajngot
    • 1
  1. 1.Department of EndocrinologyKarolinska HospitalStockholmSweden

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