Hereditary Diabetes in the KK Mouse: An Overview

  • A. S. Reddi
  • R. A. Camerini-Davalos
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 246)


Diabetes and its complications cause increased morbidity and mortality in man. Despite numerous studies, the pathogenesis of these complications is poorly understood. This is partly due to the lack of large and well-controlled human studies. To this end, researchers have been forced to develop animal models of human diabetes. In such animals, the maintenance of controlled environmental conditions and selective breeding over several generations with a large number of offspring can easily be accomplished. This allows for extensive investigation in a relatively short period of time.


Swiss Albino Mouse Oral Glucose Load Mural Cell Chemical Diabetes Fasting Blood Sugar Level 


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • A. S. Reddi
    • 1
  • R. A. Camerini-Davalos
    • 2
  1. 1.Department of MedicineUMDNJ-New Jersey Medical SchoolNewarkUSA
  2. 2.Department of MedicineNew York Medical College, Metropolitan Hospital Research CenterNew YorkUSA

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