Prediabetes pp 159-165 | Cite as

Abnormal Response to Glucose in the Prehyperglycemic Stage

  • R. A. Camerini-Davalos
  • A. S. Reddi
  • H. S. Cole
  • C. A. Velasco
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 246)


If conception marks “the beginning” of the disease, how early in life is the disease trend manifest? Even in those highly predisposed to diabetes on a genetic basis there is a period in life when the “dynamic resistance” is so effective that no abnormalities can be detected with our present capabilities and where diabetes can only be suspected. Jackson (1) called this first stage without abnormalities “suspected prediabetes” The second with detectable abnormalities (but normal carbohydrate metabolism) we recognize as prediabetes.


Blood Glucose Insulin Response Glucose Load Dynamic Resistance Immunoreactive Insulin 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • R. A. Camerini-Davalos
    • 1
  • A. S. Reddi
    • 2
  • H. S. Cole
    • 3
  • C. A. Velasco
    • 1
  1. 1.Department of MedicineNew York Medical College, Metropolitan Hospital Research CenterNew YorkUSA
  2. 2.Department of MedicineUMDNJ-New Jersey Medical SchoolNewarkUSA
  3. 3.Department of Community & Preventive Medicine, New York Medical College, Bronx Developmental CenterOMRDDUSA

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