Kinetics of Synthesis and Degradation of the Polymer Derived from Tetrachloroplatinate and Methotrexate

  • Charles E. CarraherJr.
  • Rickey E. Strothers
Part of the Polymer Science and Technology book series (PST, volume 38)

Abstract

The kinetics of formation and degradation were determined for the coordination polymer formed from tetrachloroplatinate and methotrexate. Synthesis occurs through pseudo-second order kinetics. Degradation occurs rapidly in DMSO, DMSO/H2O and as a solid in H2O. Degradation in DMSO occurs through a random scission mechanism.

Keywords

Lymphoma DMSO Platinum Fourier Transform Infrared Spectroscopy Half Life 

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Charles E. CarraherJr.
  • Rickey E. Strothers
    • 1
  1. 1.Department of ChemistryFlorida Atlantic UniversityBoca RatonUSA

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