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The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy pp 157–166Cite as

Mount Sinai Clinical Experience with Leucovorin and 5-Fluorouracil

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 244))

Abstract

The early Mount Sinai clinical experience appears to be relevant to unresolved questions concerning both leucovorin (LV) dosage and 5-fluorouracil (FU) schedules examined in the Gastrointestinal Tumor Study Group (GITSG) and Mayo Clinic-North Central trials. In addition, recent findings in the course of evolving practice provide support for specific new applications of LV-FU for combined modality and combination chemotherapy.

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References

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Authors and Affiliations

  1. Mount Sinai School of Medicine, 1 Gustave L. Levy Place, Box 1178, New York, New York, 10029, USA

    Howard W. Bruckner

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  1. Howard W. Bruckner
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Editor information

Editors and Affiliations

  1. Roswell Park Memorial Institute, Buffalo, New York, USA

    Youcef Rustum  & John J. McGuire  & 

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© 1988 Plenum Press, New York

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Bruckner, H.W. (1988). Mount Sinai Clinical Experience with Leucovorin and 5-Fluorouracil. In: Rustum, Y., McGuire, J.J. (eds) The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy. Advances in Experimental Medicine and Biology, vol 244. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-5607-3_16

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  • DOI: https://doi.org/10.1007/978-1-4684-5607-3_16

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-5609-7

  • Online ISBN: 978-1-4684-5607-3

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