Ca2+ Transport by Liver and Plant Mitochondria
Mitochondria isolated from vertebrate tissues possess a very active Ca2+ transport system that is believed to participate in the intracellular Ca2+ homeostasis. In respiring mitochondria the Ca2+ distribution between the matrix and extramitochondrial compartments, in steady state, is kinetically regulated by the simultaneous operation of two distinct pathways for Ca2+ influx and efflux. Ca2+ uptake takes place by a uniport mechanism driven electrophoretically by the negative-inside membrane potential and the efflux pathway appears to promote the electroneutral exchange of matrix Ca2+ by external Na+ or H+ (Fiskum and Lehninger, 1981; Hansford, 1985; McCormack and Denton, 1986).
KeywordsLiver Mitochondrion Plant Mitochondrion Copyright Holder Submitochondrial Particle Vertebrate Tissue
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