Neurogenesis and Maturation of Cell Morphology in the Development of the Mammalian Retina

  • Edward H. Polley
  • Roger P. Zimmerman
  • Richard L. Fortney
Part of the Perspectives in Vision Research book series (PIVR)


The cellular organization and morphology of the adult mammalian retina results from a complex series of interacting developmental events. These events may occur sequentially or simultaneously, alone or in combination. Each individual event of development may have pervasive influences that modify or direct morphogenesis of the retina as a whole, or it may have local effects on birth and differentiation of individual populations of neural and glial cells. The time period during which individual modulatory phenomena may be effective can vary with the stage of development. In this review we limit our discussion to the production of neuroblasts, the maturation of their cellular morphology, and the contributions of their processes to the structure and the circuitry of the adult mammalian retina. The role of cell death in the development of the retina is considered elsewhere in this volume (Chapters 7, 9, and 10).


Retinal Ganglion Cell Amacrine Cell Horizontal Cell Outer Nuclear Layer Inner Nuclear Layer 


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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Edward H. Polley
    • 1
  • Roger P. Zimmerman
    • 2
    • 3
  • Richard L. Fortney
    • 4
    • 5
  1. 1.Departments of Anatomy and Cell Biology, and Ophthalmology, College of MedicineUniversity of IllinoisChicagoUSA
  2. 2.Departments of Neurological Sciences and PhysiologyRush Medical CollegeChicagoUSA
  3. 3.Department of Anatomy and Cell Biology, College of MedicineUniversity of IllinoisChicagoIllinoisUSA
  4. 4.Department of Neurological SciencesRush Medical CollegeChicagoUSA
  5. 5.Department of Anatomy and Cell Biology, College of MedicineUniversity of IllinoisChicagoUSA

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