Cell Biology of the Endometrium

  • Wendell W. Leavitt


The uterus is an extremely dynamic organ the normal function of which is orchestrated by a regular procession of cellular and molecular events that occur in response to changing levels of ovarian hormones secreted during the female reproductive cycle. This is well exemplified by the human menstrual cycle as depicted in Figs. 1 and 2. The menstrual cycle is named for the one overt indication of the cyclic nature of female reproductive function, that is, the periodic discharge of blood from the vagina, which results from sloughing of the endometrium. The average menstrual cycle is 28 days in length. The first part of the cycle, the proliferative phase, is the phase when follicles grow. Ovulation occurs about midway through the cycle (day 14), and the remainder of the cycle, the secretory phase, reflects corpus luteum function.


Estrogen Receptor Progesterone Receptor Acceptor Site Human Endometrium Decidual Cell 


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Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Wendell W. Leavitt
    • 1
    • 2
  1. 1.Department of BiochemistryTexas Tech University Health Sciences CenterLubbockUSA
  2. 2.Department of Obstetrics and GynecologyTexas Tech University Health Sciences CenterLubbockUSA

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