Surgical Management of Craniopharyngiomas

Comparison of Results by Different Operative Approaches
  • Takanori Fukushima
  • Kenta Yamakawa
Part of the Contemporary Perspectives in Neurosurgery book series (COPENEU)


Craniopharyngiomas are benign, slowly growing tumors in the area of the hypothalamopituitary axis. According to data from the Japanese Brain Tumor Registry,1 in the 10-year period between 1969 and 1978 these tumors constituted 5.8% of all primary intracranial neoplasms (15,839 cases) (Fig. 1). They are seen fairly evenly at all ages, with some preponderance between the ages of 5 and 10 years (Fig. 2). Despite the advent of sophisticated microsurgical techniques, surgical management of craniopharyngiomas remains one of the most difficult and challenging subjects in neurosurgery. Although a wide variety of operative methods have been described, the optimum surgical approach continues to be a controversial issue. This report deals with our recent experience with the microsurgical treatment of 21 craniopharyngioma cases, and discussion will focus upon the comparison of our operative results by different surgical approaches and on the radicality of tumor resection.


Obesity Pneumonia Neurol Meningitis Hydrocephalus 
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  1. 1.
    The Committee of Brain Tumor Registry in Japan. Brain Tumor Registry in Japan, 1969–1981, vol. 6. Tokyo, Japan, National Cancer Center, 1987, 9–11.Google Scholar
  2. 2.
    Fukushima T, Sano K: Sublabial rhinoseptoplastic technique for transsphenoidal pituitary surgery by a hinged-septum method (technical note). J Neurosurg 1980; 52: 867–870.PubMedCrossRefGoogle Scholar
  3. 3.
    Fukushima T: Unilateral interhemispheric approach through a 3 cm trephine opening for aneurysms of the anterior cerebral artery. Presented at the 33rd Annual Meeting of the Congress of Neurological Surgeons, Chicago, 1983.Google Scholar
  4. 4.
    Carmel PW, Antunes JL, Chang CH: Craniopharyngiomas in children. Neurosurgery 1982; 11: 382–389.PubMedCrossRefGoogle Scholar
  5. 5.
    Hoffman HJ, Hendrick EB, Humphreys RP, et al: Management of craniopharyngioma in children. J Neurosurg 1977; 47: 218–227.PubMedCrossRefGoogle Scholar
  6. 6.
    Patterson RH, Danylevich A: Surgical removal of craniopharyngiomas by a transcranial approach through the lamina terminalis and sphenoid sinus. Neurosurgery 1980; 7: 111–117.PubMedCrossRefGoogle Scholar
  7. 7.
    Konig A, Ludecke DK, Herrmann HD: Transnasal surgery in the treatment of craniopharyngiomas. Acta Neurochir(Wien) 1986; 83: 1–7.CrossRefGoogle Scholar
  8. 8.
    Laws ER: Transsphenoidal microsurgery in the management of craniopharyngiomas. J Neurosurg 1980; 52: 661–666.PubMedCrossRefGoogle Scholar
  9. 9.
    Matson DD, Crigler JF: Management of craniopharyngioma in childhood. J Neurosurg 1969; 30: 377390.Google Scholar
  10. 10.
    Kramer S, McKissock W, Concannon JP: Craniopharyngiomas. Treatment by combined surgery and radiation therapy. J Neurosurg 1961; 18: 217–226.PubMedCrossRefGoogle Scholar
  11. 11.
    Kahn EA, Gosch HH, Seeger JF, et al: Forty-five years’ experience with the craniopharyngiomas. Surg Neurol 1973; 1: 5–12.PubMedGoogle Scholar
  12. 12.
    Sharma U, Tandon PN, Saxena KK: Craniopharyngiomas treated by a combination of surgery and radiotherapy. Clin Radiol 1974; 25: 13–17.PubMedCrossRefGoogle Scholar
  13. 13.
    Hoffman HJ: Craniopharyngiomas. Can J Neurol Sci 1985; 12: 348–352.PubMedGoogle Scholar
  14. 14.
    Sweet WH: Radical surgical treatment of craniopharyngioma. Clin Neurosurg 1976; 23: 52–79.PubMedGoogle Scholar
  15. 15.
    Symon L, Sprich W: Radical excision of craniopharyngioma. J Neurosurg 1985; 62: 174–181.PubMedCrossRefGoogle Scholar
  16. 16.
    Manaka S, Teramoto A, Takakura K: The efficacy of radiotherapy for craniopharyngioma. J Neurosurg 1985; 62: 648–656.PubMedCrossRefGoogle Scholar
  17. 17.
    Baskin DS, Wilson CB: Surgical management of craniopharyngiomas. J Neurosurg 1986; 65: 22–27.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Takanori Fukushima
    • 1
  • Kenta Yamakawa
    • 1
  1. 1.Department of Neurological SurgeryMitsui Memorial HospitalChiyoda-Ku, TokyoJapan

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