The adenoviruses of humans, of which there are now 41 serotypes, are naked icosahedrons, 70–90 nm in diameter, and contain a genome composed of linear double-stranded DNA. They are associated with a wide spectrum of diseases (Table I) and they have been isolated from virtually all organs, but they are primarily regarded as common pathogens of the respiratory tract and eye. Most individuals become infected early in life with at least several sero types. To a certain extent, the kinds of adenovirus-associated diseases to which people become susceptible change as they grow older; each of these illnesses is caused by a limited number of serotypes. With rare exceptions, adenovirus infections are short-lived and self-limited.
KeywordsAcquire Immune Deficiency Syndrome Adenovirus Infection Adenovirus Type Human Adenovirus Severe Combine Immunodeficiency Disease
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