The Potential of Membrane-Acting Toxins for Targeted Cancer Therapy
Cell membrane-disrupting toxins (cytolysins) have great appeal as candidates for targeting to tumor cells by means of monoclonal antibodies, yet their use has been explored in only a few studies to date. Here, we appraise the potential of antibody-cytolysin conjugates, or ‘immunolysins’ for cancer therapy.
KeywordsClostridium Perfringens Peptide Toxin Cobra Venom Factor Imperial Cancer Research Fund Friend Leukaemia Cell
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