The Potential of Membrane-Acting Toxins for Targeted Cancer Therapy

  • Francis A. Drobniewski
  • Philip E. Thorpe
  • Philip M. Wallace
  • Edward J. Wawrzynczak
Part of the NATO ASI Series book series (NSSA, volume 155)


Cell membrane-disrupting toxins (cytolysins) have great appeal as candidates for targeting to tumor cells by means of monoclonal antibodies, yet their use has been explored in only a few studies to date. Here, we appraise the potential of antibody-cytolysin conjugates, or ‘immunolysins’ for cancer therapy.


Clostridium Perfringens Peptide Toxin Cobra Venom Factor Imperial Cancer Research Fund Friend Leukaemia Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Francis A. Drobniewski
    • 1
  • Philip E. Thorpe
    • 1
  • Philip M. Wallace
    • 1
  • Edward J. Wawrzynczak
    • 2
  1. 1.Drug Targeting LaboratoryImperial Cancer Research FundLondonUK
  2. 2.Institute of Cancer ResearchThe Haddow LaboratoriesSutton, SurreyUK

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