Reconstituted Influenza Virus Envelopes as a Potential Carrier for Fusion-Mediated Microinjection of Macromolecules into Living Cells
The process of virus-membrane fusion mediates penetration of most enveloped virions into animal cells (White et al, 1983). Fusion between the viral envelopes and membrane of recipient cells results in microinjection of the viral nucleocapsid into the cells’ cytoplasm.
KeywordsInfluenza Virion Virus Envelope Trapping Efficiency Sendai Virus Intact Virion
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- Loyter, A., and Volsky, D. J., 1982, Reconstituted Sendai virus envelopes as carriers for the introduction of biological material into animal cells, in: “Membrane Reconstitution,” Poste, G., and Nicolson, G. L., eds., Elsevier/North Holland, Biomedical Press, Amsterdam.Google Scholar
- Loyter, A., Gitman, A. G., Chejanovsky, N., and Nussbaum, O., 1986, Fusion-mediated microinjection of macromolecules into living cultured cells by “targeted” Sendai virus envelopes, in: “Microinjection and Organelle Transplantation Techniques,” J. E. Cellis, A. Graessman and. Loyter, eds., Academic Press, New York.Google Scholar
- Poste, G., and Pasternak, C. A., 1978, Virus induced cell fusion, in: “Cell Surface Reviews: Membrane Fusion,” G. Poste and G. L. Nicolson, eds., Vol. 5, North Holland Publishing Co., Amsterdam.Google Scholar
- Scherphof, G. L., Spanjer, H. H., Dijkstra, J., Derksen, J. T. P., and Roerdnik, F. H., 1986, Participation of Kupffer cells and Hepato-cytes, in: “Hepatic Uptake and Processing of Liposomes, in Medical Application of Liposomes,” K. Yagi, ed., Japan Scientific Societies Press, Tokyo.Google Scholar
- Vainstein, A., Rzin, A., Graessmann, A., and Loyter, A., 1983, Fusogenic reconstituted Sendai virus envelopes as a vehicle for introduction DNA into viable mammalian cells, Meth. 101:492.Google Scholar