Targeting of Antigens to Antigen-Presenting Cells and their Activation: A Requirement for Vaccine Development

  • Anthony C. Allison
  • Noelene E. Byars
Part of the NATO ASI Series book series (NSSA, volume 155)


The efficacy of vaccination was illustrated in a dramatic way by the global eradication of smallpox ten years ago. Vaccination has also greatly reduced morbidity and mortality due to yellow fever in Africa and Central America. In the United States vaccination programs have nearly eliminated deaths from diphtheria, measles and mumps as well as paralytic poliomyelitis and the congenital rubella syndrome (Hilleman, 1985).


Genital Herpes Follicular Dendritic Cell MURAMYL Dipeptide Congenital Rubella Syndrome Aluminum Phosphate 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Anthony C. Allison
    • 1
  • Noelene E. Byars
    • 1
  1. 1.Department of ImmunologyInstitute of Biological Sciences Syntex ResearchPalo AltoUSA

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