Targeting of Antigens to Antigen-Presenting Cells and their Activation: A Requirement for Vaccine Development
The efficacy of vaccination was illustrated in a dramatic way by the global eradication of smallpox ten years ago. Vaccination has also greatly reduced morbidity and mortality due to yellow fever in Africa and Central America. In the United States vaccination programs have nearly eliminated deaths from diphtheria, measles and mumps as well as paralytic poliomyelitis and the congenital rubella syndrome (Hilleman, 1985).
KeywordsGenital Herpes Follicular Dendritic Cell MURAMYL Dipeptide Congenital Rubella Syndrome Aluminum Phosphate
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