Preclinical and Clinical Effects of the Hematopoietic Colony Stimulating Factors

  • Hal E. Broxmeyer
  • Saroj Vadhan-Raj
  • Giao Hangoc
  • Li Lu
  • Jordan U. Gutterman
  • Douglas E. Williams
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 34)


Hematopoietic colony stimulating factors are available in purified recombinant form and have used for assessment of hematopoietic activities in mice, monkeys and in phase I clinical trials with humans. This report reviews the preclinical and clinical studies involving these factors.


Recombinant Human Tumor Friend Virus Infectivity Human Macrophage Colony Stimulate Factor Poietic Progenitor Cell Hematopoietic Colony Stimulate Factor 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Hal E. Broxmeyer
    • 1
    • 2
  • Saroj Vadhan-Raj
    • 3
  • Giao Hangoc
    • 1
  • Li Lu
    • 1
  • Jordan U. Gutterman
    • 3
  • Douglas E. Williams
    • 1
  1. 1.Department of Medicine (Hematology/Oncology)Indiana University School of MedicineIndianapolisUSA
  2. 2.Walther Oncology CenterIndiana University School of MedicineIndianapolisUSA
  3. 3.Department of Clinical Immunology and Biological TherapyUniversity of Texas M.D. Anderson Hospital and Tumor InstituteHoustonUSA

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