Antiinflammatory, Analgesic, and Antiulcer Activities of Copper Complexes Suggest Their Use in a Physiologic Approach to Treatment of Arthritic Diseases

  • John R. J. Sorenson
Part of the Basic Life Sciences book series (BLSC, volume 49)


Copper is an essential metalloelement, and therefore is required by all human cells for normal metabolism. Amounts of copper found in various body tissues and fluids have been tabulated elsewhere.1 Calculated amounts of ionic copper suggested to be present in biological systems (10-18 M in plasma) are too small to be measured using the most sensitive instrumentation available. As a result, measurable tissue copper content reflects content of copper complexes, and these complexes account for absorption, distribution, and biologically active forms, including copper-dependent enzymes.1,2


Copper Complex Copper Chloride Copper Acetate Niflumic Acid Effective Analgesic 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • John R. J. Sorenson
    • 1
  1. 1.Division of Medicinal Chemistry, College of PharmacyUniversity of Arkansas for Medical SciencesLittle RockUSA

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