The Isolation and Partial Characterization of Stable H2O2-Resistant Variants of Chinese Hamster Fibroblasts
Several groups have reported that bacteria exposed to H2O2 are capable of adapting to H2O2-mediated cytotoxicity.1–3 The adaptation is accompanied by a shift in relative rates of protein synthesis, increased antioxidant enzymatic activity, and increased resistance to other oxidizing agents and radiation.1–4 This adaptation phenomenon has been suggested to be a general response to oxidative stress common to all bacteria.1
KeywordsCatalase Activity Adaptation Phenomenon Chinese Hamster Fibroblast Density Artifact Catalase Isozyme
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- 8.H. Aebi, Catalase in vitro, in: “Methods in Enzymology,” Academic Press, Inc. 105:121 (1984).Google Scholar