Role of Hemin in Oxidative Stress Induced by Divicine in Vitamin E-Deficient Rats

  • M. D’Aquino
  • G. Tomassi
Part of the Basic Life Sciences book series (BLSC, volume 49)


Previous results obtained with erythrocytes of vitamin E + vitamin B2 deficient rats or vitamin B2-deficient rats incubated in presence of divicine (the hemolytic factor of the favism) have shown peroxidation of membrane lipid during hemolysis,1 and decrease in the fluidity of the hydrophobic region of membrane lipids.2 These modifications appear only in the whole erythrocytes, but not when the ghosts are used (unpublished data).


Lipid Core Control Control Mouse Erythrocyte Thiobarbituric Acid Test Methemoglobin Formation 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • M. D’Aquino
    • 1
  • G. Tomassi
    • 1
  1. 1.Istituto Nazionale della NutrizioneRomeItaly

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