Membrane Permeability and Oxidant Induced Injury
This discussion concerns the mechanisms whereby cell functions are compromised by exposure to oxidant stress. One of our principal objectives is to also address the manner in which many of the studies of oxidant stress are performed, that being the use of lactate dehydrogenase (LDH) release as a marker of cell injury and use of millimolar and higher concentrations of peroxides.
KeywordsGlutathione Peroxidase Alveolar Macrophage Respiratory Burst Phorbol Myristate Acetate Sulfur Amino Acid
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- 9.H. J. Forraan, R. J. Dorio, and D. C. Skelton, Hydroperoxide induced damage to alveolar macrophage function and membrane integrity: alterations in intracellular free Ca2+ and membrane potential. Arch. Biochem. Biophys. (in press), 1987.Google Scholar