Membrane Permeability and Oxidant Induced Injury

  • Henry Jay Forman
  • Dianne C. Skelton
  • George A. Loeb
  • Raymond J. Dorio
Part of the Basic Life Sciences book series (BLSC, volume 49)


This discussion concerns the mechanisms whereby cell functions are compromised by exposure to oxidant stress. One of our principal objectives is to also address the manner in which many of the studies of oxidant stress are performed, that being the use of lactate dehydrogenase (LDH) release as a marker of cell injury and use of millimolar and higher concentrations of peroxides.


Glutathione Peroxidase Alveolar Macrophage Respiratory Burst Phorbol Myristate Acetate Sulfur Amino Acid 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Henry Jay Forman
    • 1
  • Dianne C. Skelton
    • 1
  • George A. Loeb
    • 1
  • Raymond J. Dorio
    • 1
  1. 1.Departments of Pediatrics and Pathology and Institute of Toxicology, University of Southern CaliforniaChildrens Hospital of Los AngelesLos AngelesUSA

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