Monitoring the Interactions of Environmental Agents by Cell-Dependent Chemiluminescence: Studies with Polycyclic Aromatic Hydrocarbons

  • Lorraine E. Twerdok
  • Michael A. Trush
Part of the Basic Life Sciences book series (BLSC, volume 49)


The potential toxic effects of synthetic and naturally occuring substances on human health is of increasing concern. Thus, there is a great deal of interest in the development and application of techniques to monitor the cellular interactions of xenobiotics. The generation of chemiluminescence (CL) represents a potentially powerful probe for examining chemical-cell interactions, especially when it is correlated with other monitors of cellular function or used in conjunction with other analytical techniques.1


Polycyclic Aromatic Hydrocarbon Aplastic Anemia Potential Toxic Effect Neutrophilic Cell Specific Target Cell 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Lorraine E. Twerdok
    • 1
  • Michael A. Trush
    • 1
  1. 1.Department of Environmental Health Sciences, Division of Toxicological SciencesJohns Hopkins UniversityBaltimoreUSA

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