Role of Oxygen Radicals in Endotoxin Shock and Disseminated Intravascular Coagulation
The generation of oxygen free radicals seems to be implicated in the pathogenesis of shock and disseminated intravascular coagulation (DIC) caused by endotoxin1,2, Radical generation is increased in some critical states directly related to shock and DIC, such as tissue hypoxia3, incomplete ischemia and tissue reperfusion4, activation of arachidonic acid cascade5, and complement-induced granulocyte aggregation6.
KeywordsDisseminate Intravascular Coagulation Disseminate Intravascular Coagulation Monocarboxylic Acid Endotoxin Shock Fibrin Degradation Product
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