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Superoxide Generation of Phagocytizing Polymorphonuclear Leukocytes from Patients with Chronic Renal Failure

  • Toru Tanigawa
  • Toshikazu Yoshikawa
  • Norimasa Yoshida
  • Shigeru Sugino
  • Motoharu Kondo
Part of the Basic Life Sciences book series (BLSC, volume 49)

Abstract

Patients with chronic renal failure (CRF) are susceptible to microorganisms and often suffer from severe infection. Whether this is caused in part by decreased generation of active oxygen by polymorphonuclear leukocytes (PMN) is unclear. Active oxygen generation by PMN in CRF has been reported to be augumented (NBT reduction assay),1 normal (NBT reduction assay, cytochrome C reduction assay),2,3 decreased (luminol-dependent chemiluminescence).3

Keywords

Uric Acid Chronic Renal Failure Xanthine Oxidase Polymorphonuclear Leukocyte Active Oxygen Species 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Refferences

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Toru Tanigawa
    • 1
  • Toshikazu Yoshikawa
    • 1
  • Norimasa Yoshida
    • 1
  • Shigeru Sugino
    • 1
  • Motoharu Kondo
    • 1
  1. 1.First Department of MedicineKyoto Prefectual University of MedicineKyotoJapan

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