The Respiratory Burst Oxidase

  • Bernard M. Babior
Part of the Basic Life Sciences book series (BLSC, volume 49)


Neutrophils are phagocytic cells whose major function is the ingestion and destruction of invading microorganisms. On exposure to certain stimuli, these cells begin to manufacture large quantities of microbicidal oxidants through a metabolic event known as the “respiratory burst” (reviewed in reference 1). The key reaction in the respiratory burst is the one-electron reduction of oxygen to •O2 - at the expense of a reduced pyridine nucleotide (eq. 1).


NADPH Oxidase Human Neutrophil Respiratory Burst Chronic Granulomatous Disease Sodium Dodecylsulfonate 
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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Bernard M. Babior
    • 1
  1. 1.Research Institute of Scripps ClinicLa JollaUSA

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