Microinjection of Antioxidant Enzymes to Protect Cells from Oxygen Derived Free Radicals
In recent years, there have been many reports on the protective effect of superoxide dismutase (SOD), catalase and glutathione peroxidase (Gpx) in preventing oxidative damages induced by a variety of toxic agents or occuring in pathological conditions . Despite all these works, the relative importance of each of these antioxidant enzymes is not yet well established. We undertook the present study in order to determine the respective efficiency of these three enzymes in protecting human fibroblasts against oxygen-derived free radicals generated either by oxygen or by nitrofurantoin.
KeywordsGlutathione Peroxidase Oxygen Toxicity Human Diploid Fibroblast Free Radical Attack Enzyme Subunit
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