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Early Alterations in Striatal and Hippocampal Impedance and Extracellular Amino Acids by Cardiac Arrest in Freely Moving Rats

  • J. Korf
  • H. C. Klein
  • K. Venema
  • F. Postema
Part of the Advances in Behavioral Biology book series (ABBI, volume 35)

Abstract

The time course of changes in the tissue impedance and the extracellular transmitter- and non-transmitter amino acids were studied in the striatum and the hippocampus of the unanesthetized rat after cardiac arrest. Electrodes were implanted for the continuous measurement of tissue impedance to provide a measure of the volume of extracellular space. Alternatively bilateral dialysis probes were utilized to monitor extracellular amino acids in subsequent 30s samples using an automated pre-column derivatization technique for reversed phase HPLC analysis and fluorimetric detection.

Keywords

Cardiac Arrest Amino Acid Uptake Tissue Impedance Fluorimetric Detection Derivatization Technique 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • J. Korf
    • 1
  • H. C. Klein
    • 1
  • K. Venema
    • 1
  • F. Postema
    • 1
  1. 1.Dept. Biological PsychiatryUniversity Psychiatric ClinicGroningenThe Netherlands

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