The Human Genome Project: A DOE Perspective
The structural characterization of genes and elucidation of their encoded functions has become a cornerstone of modern biology and biotechnology. But of the estimated 100,000 human genes, only some 1,500 are represented as mapped genes and markers, cloned DNA segments, fragile sites, cloned genes, and neoplasia-associated break points. To assess the desirability and feasibility of ordering and sequencing clones representing the entire human genome by the year 2000, an ambitious goal, the Office of Health and Environmental Research (OHER) of the Department of Energy (DOE) sponsored in March 1986 an international meeting in Santa Fe, New Mexico. The participating experts concluded with virtual unanimity that this objective was meritorious, technically obtainable and would be an outstanding achievement in modern biology. Further guidance was sought from the Health and Environmental Research Advisory Committee (HERAC) of the DOE, which provided its report on the Human Genome Initiative in April of 1987.
KeywordsEuropean Economic Community Modern Biology Computer Mediate Communication Entire Human Genome National Research Council Report
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