High Resolution Electron Microscopy for Structure and Mapping

  • James F. Hainfeld
  • Joseph S. Wall
Conference paper

DOI: 10.1007/978-1-4684-5547-2_13

Part of the Basic Life Sciences book series (BLSC, volume 46)
Cite this paper as:
Hainfeld J.F., Wall J.S. (1988) High Resolution Electron Microscopy for Structure and Mapping. In: Woodhead A.D., Barnhart B.J., Vivirito K. (eds) Biotechnology and the Human Genome. Basic Life Sciences, vol 46. Springer, Boston, MA

Abstract

Electron microscopes are very valuable to the human genome project. Brookhaven’s Scanning Transmission Electron Microscope (STEM) is unique in many respects. It is like the National Synchrotron Light Source (NSLS) or the High Flux Beam Reactor (HFBR) at Brookhaven, but on a much smaller scale. The STEM uses electrons that are focussed through the sample, and detected. It is a scanning microscope because it scans the beam much like a television set. This is in contrast to most electron microscopes that are fixed beam, flood the sample with electrons, and then use a lens after the sample that reimages the material at higher magnification. There are some advantages of scanning, which I will describe.

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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • James F. Hainfeld
    • 1
  • Joseph S. Wall
    • 1
  1. 1.Biology DepartmentBrookhaven National LaboratoryUptonUSA

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