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Selection and Utilization of Monoclonal Antibody Defined Melanoma Associated Antigens for Immunoscintigraphy in Patients with Melanoma

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Radiolabeled Monoclonal Antibodies for Imaging and Therapy

Part of the book series: NATO ASI Series ((NSSA,volume 152))

Abstract

Analysis of human melanoma cells with murine monoclonal antibodies has identified a number of antigens which are associated with the malignant transformation of melanocytes (for review, see 1,2). These antigens are referred to as melanoma associated antigens (MAA). Most of them, if not all of them, are detectable in melanocytes which are cultured in-vitro and are likely to be differentiation antigens.

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Authors and Affiliations

  1. Department of Microbiology and Immunology, New York Medical College, Valhalla, NY, USA

    S. Ferrone, M. Temponi & D. Gargiulo

  2. Research Center, Sorin Biomedica, Saluggia, Italy

    G. A. Scassellati

  3. Department of Surgery, Regina Elena Cancer Institute, Rome, Italy

    R. Cavaliere

  4. Laboratory of Immunology, Regina Elena Cancer Institute, Rome, Italy

    P. G. Natali

Authors
  1. S. Ferrone
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  2. M. Temponi
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  3. D. Gargiulo
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  4. G. A. Scassellati
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  5. R. Cavaliere
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  6. P. G. Natali
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Editors and Affiliations

  1. Brookhaven National Laboratory, Upton, New York, USA

    Suresh C. Srivastava

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Ferrone, S., Temponi, M., Gargiulo, D., Scassellati, G.A., Cavaliere, R., Natali, P.G. (1988). Selection and Utilization of Monoclonal Antibody Defined Melanoma Associated Antigens for Immunoscintigraphy in Patients with Melanoma. In: Srivastava, S.C. (eds) Radiolabeled Monoclonal Antibodies for Imaging and Therapy. NATO ASI Series, vol 152. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5538-0_5

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